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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nogr</journal-id><journal-title-group><journal-title xml:lang="ru">Экспериментальная и клиническая гастроэнтерология</journal-title><trans-title-group xml:lang="en"><trans-title>Experimental and Clinical Gastroenterology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-8658</issn><publisher><publisher-name>«Global Media Technologies»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31146/1682-8658-ecg-169-9-101-106</article-id><article-id custom-type="elpub" pub-id-type="custom">nogr-1240</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ НАБЛЮДЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASES</subject></subj-group></article-categories><title-group><article-title>Сочетания язвенного колита и инфекционного эндокардита</article-title><trans-title-group xml:lang="en"><trans-title>Сombination of ulcerative colitis and infectious endocarditis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6581-7017</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ливзан</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Livzan</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ливзан Мария Анатольевна, д. м. н., профессор, ректор, заведующая кафедрой факультетской терапии, профессиональных болезней, 644099, Россия, г. Омск, ул. Ленина, 12</p></bio><bio xml:lang="en"><p>Mariya A. Livzan, doctor of medical sciences, professor, rector, head of the department of faculty therapy, occupationaldiseases, 12 Lenina str., Omsk, 644099, Russia</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гылка</surname><given-names>Д. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Gylka</surname><given-names>D. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гылка Дарья Сергеевна, клинический ординатор кафедры факультетской терапии, профессиональных болезней, 644099, Россия, г. Омск, ул. Ленина, 12</p></bio><bio xml:lang="en"><p>Darya S. Gylka, clinical resident of the department of faculty therapy, occupational diseases, 12 Lenina str., Omsk, 644099, Russia</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6225-2444</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Скирденко</surname><given-names>Ю. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Skirdenko</surname><given-names>Yu. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Скирденко Юлия Петровна, к. м. н., ассистент кафедры факультетской терапии, профессиональных болезней, 644099, Россия, г. Омск, ул. Ленина, 12</p></bio><bio xml:lang="en"><p>Yuliya P. Skirdenko, cand. of med. sci, assistant of the Department of faculty therapy, occupational diseases, 12 Lenina str., Omsk, 644099, Russia</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3758-4930</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Николаев</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikolaev</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Николаев Николай Анатольевич, д. м. н., доцент, проректор по медицинской деятельности и региональному здравоохранению, профессор кафедры факультетской терапии, профессиональных болезней, 644099, Россия, г. Омск, ул. Ленина, 12</p></bio><bio xml:lang="en"><p>Nikolaj A. Nikolaev, doctor of medical sciences, associate professor, vice-rector for medical activity and regional health care, professor of the department of faculty therapy, occupational diseases, 12 Lenina str., Omsk, 644099, Russia</p></bio><email xlink:type="simple">niknik.67@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ратникова</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ratnikova</surname><given-names>O. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ратникова Ольга Александровна, врач-гастроэнтеролог, 644046, Россия, г. Омск, проспект Космический, д. 99</p></bio><bio xml:lang="en"><p>Olga A. Ratnikova, doctor-gastroenterologist, 644046, Russia, Omsk, prospect Kosmicheskiy, 99</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Омский государственный медицинский университет» МЗ РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Omsk state medical University, Ministry of health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>БУЗ ОО Городская больница № 17</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City hospital № 17</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>24</day><month>03</month><year>2020</year></pub-date><volume>0</volume><issue>9</issue><fpage>101</fpage><lpage>106</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ливзан М.А., Гылка Д.С., Скирденко Ю.П., Николаев Н.А., Ратникова О.А., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Ливзан М.А., Гылка Д.С., Скирденко Ю.П., Николаев Н.А., Ратникова О.А.</copyright-holder><copyright-holder xml:lang="en">Livzan M.A., Gylka D.S., Skirdenko Y.P., Nikolaev N.A., Ratnikova O.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nogr.org/jour/article/view/1240">https://www.nogr.org/jour/article/view/1240</self-uri><abstract><p>В статье представлен клинический случай сочетания язвенного колита и инфекционного эндокардита двустворчатого аортального клапана. Наличие такого сочетания представляет большую сложность для курации, в первую очередь, вследствие высокого риска осложнений, связанных с особенностями специфической терапии этих заболеваний и значимо влияющих на качество жизни и прогноз. Очевидна необходимость накопления знаний о развитии и течении кардиоваскулярных заболеваний у больных язвенным колитом и уточнение патофизиологических механизмов таких состояний.</p></abstract><trans-abstract xml:lang="en"><p>The article presents a clinical case of a combination of ulcerative colitis and infectious endocarditis of the bicuspid aortic valve. The presence of such a combination is very difficult for the curation, primarily due to the high risk of complications associated with the peculiarities of specific therapy of these diseases and significantly affect the quality of life and prognosis. It is obvious that there is a need to accumulate knowledge about the development and course of cardiovascular diseases in patients with ulcerative colitis and to clarify the pathophysiological mechanisms of such conditions.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>язвенный колит</kwd><kwd>инфекционный эндокардит</kwd><kwd>клинический случай</kwd><kwd>внекишечные проявления</kwd></kwd-group><kwd-group xml:lang="en"><kwd>ulcerative colitis</kwd><kwd>infectious endocarditis</kwd><kwd>clinical case</kwd><kwd>extra-intestinal manifestations</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Кляритская И. Л., Стилиди Е. И., Максимова Е. В. и др. Внекишечные проявления воспалительных заболеваний кишечника. Крымский терапевтический журнал 2017;1:47–51.</mixed-citation><mixed-citation xml:lang="en">Kliaritskaia I. L., Stilidi. E.I., Maksimova E. V.et al. 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