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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nogr</journal-id><journal-title-group><journal-title xml:lang="ru">Экспериментальная и клиническая гастроэнтерология</journal-title><trans-title-group xml:lang="en"><trans-title>Experimental and Clinical Gastroenterology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1682-8658</issn><publisher><publisher-name>«Global Media Technologies»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31146/1682-8658-ecg-172-12-90-94</article-id><article-id custom-type="elpub" pub-id-type="custom">nogr-1217</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW</subject></subj-group></article-categories><title-group><article-title>Влияние инфекции Helicobacter pylori на течение неалкогольной жировой болезни печени</article-title><trans-title-group xml:lang="en"><trans-title>Effect of Helicobacter pylori infection on the course of nonalcoholic fatty liver disease</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лазебник</surname><given-names>Л. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Lazebnik</surname><given-names>L. B.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тарасова</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Tarasova</surname><given-names>L. V.</given-names></name></name-alternatives><email xlink:type="simple">tlarisagast18@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Комарова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Komarova</surname><given-names>E. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бусалаева</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Busalayeva</surname><given-names>E. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Московский государственный медицинский стоматологический университет им. А. И. Евдокимова»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>FSEBI of HE “A. I. Evdokimov Moscow State University of Medicine and Dentistry” of the Ministry of Healthcare of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Чувашский государственный университет им. И. Н. Ульянова»; БУВО ХМАО-Югры «Сургутский государственный университет»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>FSEBI of HE “The Ulianov Chuvash State University”; EI of HE “The Surgut State University”</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБОУ ВО «Чувашский государственный университет им. И. Н. Ульянова»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>FSEBI of HE “The Ulianov Chuvash State University”</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ФГБОУ ВО «Чувашский государственный университет им. И. Н. Ульянова»; ГАУ ДПО «Институт усовершенствования врачей» Министерства здравоохранения Чувашской Республики</institution><country>Россия</country></aff><aff xml:lang="en"><institution>FSEBI of HE “The Ulianov Chuvash State University”; SAI APE “Postgraduaute Medical Institute” of the Ministry of Health of the Chuvash Republic</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>20</day><month>12</month><year>2019</year></pub-date><volume>0</volume><issue>12</issue><fpage>90</fpage><lpage>94</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Лазебник Л.Б., Тарасова Л.В., Комарова Е.А., Бусалаева Е.И., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Лазебник Л.Б., Тарасова Л.В., Комарова Е.А., Бусалаева Е.И.</copyright-holder><copyright-holder xml:lang="en">Lazebnik L.B., Tarasova L.V., Komarova E.A., Busalayeva E.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.nogr.org/jour/article/view/1217">https://www.nogr.org/jour/article/view/1217</self-uri><abstract><p>Распространенность неалкогольной жировой болезни печени (НАЖБП) в мире неуклонно растет, превратив ее за последнее десятилетие в самую распространенную патологию печени. Являясь мультидисциплинарной проблемой, НАЖБП привлекает внимание специалистов различных профилей. Особый интерес вызывает прояснение основных звеньев патогенеза неалкогольной жировой болезни печени, в том числе вопрос влияния эндогенной микрофлоры на возникновение и течение заболевания. В обзоре приведены современные данные, подтверждающие наличие взаимосвязи между инфекцией Helicobacter pylori (H. Pylori) и НАЖБП. Доказано, что успешная эрадикация H. Pylori, замедляет процессы фиброобразования в печени, снижает уровень провоспалительных маркеров и улучшает инсулинорезистентность.</p></abstract><trans-abstract xml:lang="en"><p>The prevalence of nonalcoholic fatty liver disease (NAFLD) in the world steadily increasеs, turning it into a most prevalent liver disease in the last decade. NAFLD is a multidisciplinary problem, it attracts the attention of specialists of different specialities. Especially interesting is the clarification of the main links of the pathogenesis of nonalcoholic fatty liver disease, including the effect of endogenous microflora on the occurrence and course of disease. Modern information is represented in the review, it confirm the association between Helicobacter pylori infection (H. pylori) and NAFLD. It has been proven that successful eradication of H. pylori detaines the fibrosis in the liver, reduces the level of proinflammatory markers, and improves insulin resistance.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>неалкогольная жировая болезнь печени</kwd><kwd>Helicobacter pylori</kwd><kwd>инсулинорезистентость</kwd><kwd>эрадикация</kwd><kwd>nonalcoholic fatty liver disease</kwd><kwd>Helicobacter pylori</kwd><kwd>insulin resistance</kwd><kwd>eradication</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
